The Africa Health Research Organization in conjunction with its partner under the sponsorship of Dafra Pharma International Ltd welcomes you to:
1 st AHRO International Malaria Symposium on Clinical Pharmacology of Antimalarial Drugs
Dates: 12-13 August 2008.
Programme Overview
| 11th August MONDAY |
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Pre-symposium Events
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| 10:00 am - 11:00 am |
Welcome Interactive Sessions
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| 11:00 am - 16:00 pm |
Social Events: “ Take off the white coats ”
Tour includes visit to the Dzorwulu School of the Handicapped, Elmina Castle and
Kwame Nkrumah Memorial Park .
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| 16:00 pm - 17:00 pm |
Lectures by Dr Volker on Vaccine Strategies and Prof Nadira on Antimalarial resistance
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| 12th August, 2008 TUESDAY |
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| 7:30 am - 8:30 am |
Breakfast
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| AM |
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Opening Lectures: The Present Global Perspective
Chair: Professor Jean-Bosco Quegraogo(IRSS, Burkina Faso)
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| 9:00 am - 9:15 am |
Welcome to Speech
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| 9:15 am - 9:45 am |
Professor Boaz Adegboro (University Of Ilorin, Nigeria)
“Recent Advances in the treatment of Malaria Infection”
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| 9:45 am - 10:15 am |
Dr James-Paul Kretchy (University of Ghana Medical School)
“Microvascular Damage, Variant Surface Antigens and Pathogenesis of Severe Malaria
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| 10:15 am - 10.45 am |
Dr Ebenezer Inkoom (UNICEF, Ghana)
“Reducing Malaria –associated mortalities- role of effective treatment”
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| 10:45 am - 11:15 am |
Dr Joaquim Sewaka (WHO Representative in Ghana)
“The burden of Malaria Drug resistance”
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| 11:15 am - 11:30 am |
Coffee Break
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Session 1: Pharmacokinetics & Pharmacodynamics of Antimalarial Drugs
Chairperson: Professor Wilfred Mbacham (University of Yaoundé, Cameroon)
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| 11:30 am - 12:00 nn |
Dr FH Jansen (R&D Director, Dafra Pharma Ltd, Belgium )“Resistance to Partner drugs in ACT's: A critical appraisal of the Paradox”
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| 12:00 nn - 12:30 pm |
Dr Sergio Giani (Aids To Development Of Traditional Medicine, Mali) “Malaria & Traditional Medicine in Mali ”
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| 12:30 pm - 13:00 pm |
Dr I Ikeh (Ebonyi State University, Nigeria)
“Assessment of the efficacy of synergistic combination of Pyrimethamine and Sulfadoxine (Maloxine) in Abakaliki Ebonyi State Nigeria”
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| 13:00 pm - 13:30 pm |
Dr TF Muanda (University of Kinshasa, DRC)
“Assessment of rational use of ACT in Kinshasa, DRC”
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| 13:30 pm - 14:00 pm |
Professor Issaka Sagara (University of Bamako)
“Typical African diets: fat content and absorption of artemether-lumefantrine”
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| 14:00 pm - 14:30 pm |
Professor Larry Fleckenstein (University of Iowa, USA)
“Pharmacokinetic of Pyronaridine/ Artesunate (Pyramax): A new ACT”
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| 14:30 pm - 15:00 pm |
Panel Discussion
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| 15:00 pm - 16:30pm |
Lunch & Interactive session
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| PM |
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Session 2 : Treatment of Complicated and Uncomplicated Malaria & Co-infections
Chair: Professor Hamza Babiker (University of Edinburgh , Scotland & Sultan Qaboos
University, Oman)
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| 17:00 pm – 17:30 pm |
Dr Jorgen Kurtzhals (University of Copenhagen, Denmark)
“Adjunct Treatment for Complicated Malaria: Past Disappointment, Future Promises”
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| 17:30 pm -18:00 pm |
Dr TF Muanda (University of Kinshasa, DRC)
“Strategies for improving the use of ACT in the treatment of uncomplicated malaria in DRC”
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| 18:00 pm – 18:30 pm |
Dr Catherine O Falade (University of Ibadan , Nigeria)
“IPT with SP As Effective Strategy To Prevent Maternal & Placental Malaria”
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18:30pm - 19:00pm |
Professor Wilfred Mbacham (University Of Yaoundé, Cameroun)
“Therapeutic efficacy of Fansider & Antifolate resistance gene in two ecological zones
In Cameroon”
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| 19:00pm- 19:30pm |
Panel Discussion
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| 19:30pm-19:45pm |
Coffee Break
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Session 3: Drug Combination & Interaction in Malaria
Chair: Professor Francine Ntoumi (MIM Secretariat Co-coordinator, Tanzania)
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| 19:45pm - 20:15pm |
Dr George Obeng Adjei (Korle-Bu Teaching Hospital, Ghana)
“Amodiaquine alone or in combination with Artesunate or co-arthemether: Efficacy Pharmacokinetics, safety and molecular markers in Children reporting to Korle-Bu Hospital”
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| 20:15pm - 20:45pm |
Dr FH Jansen (R&D Director, Dafra Pharma Ltd, Belgium )
“Fixed dose combination in the treatment of Malaria: Role of partner drug”
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| 20:45pm - 21:15pm |
Professor Ib C Bygberg ( University of Copenhagen , Denmark )
“Taking Laboratory Research into Clinical & Public Health: The case of resistance and interactions of antimalarials”
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| 21:15pm - 22:15pm |
Panel Discussion
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| 22:15pm-22:30pm |
Closing Remark
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| 22:30 pm |
First Day Closes
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| 13th August, 2008 WEDNESDAY |
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| AM |
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Session 4: Drug Resistance
Chair: Professor Larry Fleckenstein (Iowa University, USA)
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| 9:30 am - 10:00 am |
Professor AP Dash (National Malaria Institute of Research, India)
“Drug Resistance in India”
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| 10:00am- 10:30am: |
Dr Olukemi Amodu (University of Ibadan)
“Ineffective Antimalarial is deleterious in the outcome of severe malaria”
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| 10:30-10:45am |
Coffee Break
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| 10:45am-11:15am |
Professor Hamza Babiker (University of Edinburgh, Scotland & Sultan Qaboos University, Oman)
“Compromised Fitness of Drug Resistance Plasmodium Falciparum Parasites
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| 11:15am- 11:45pm |
Dr Motalalepula G Matsabisa (Medical Research Council, South Africa)
“Chloroquine: In vitro Activities & Resistance Reversal”
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| 11:45am-12:15pm |
Professor Jean-Bosco Ouegraogo (IRSS, Burkina Faso)
“ACTs and Recurrent Malaria Infection in West Africa”
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| 12:15pm- 13:30pm |
Panel Discussion
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| 13:30pm-14:30pm |
Lunch Break & Interactive Session
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| PM |
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Satellite Meeting by Dafra Pharma International
Chair: Professor Nadira Karunaweera University of Colombo
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| 14:30pm-15:30pm |
Topic Confirmed
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Session 5: Clinical Trials
Chair: Professor Ib C Bygberg (University of Copenhagen, Denmark)
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| 15:30pm – 16:00pm |
Dr Charles Mutai (Kenya Medical Research Institute, Kenya)
“In vivo Screening of Antimalarial Activity of Acacia Mellifera (Leguminosae) on Plasmodium Berghei in mice
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| 16:00pm-16:30pm |
Dr Kolawole Olatunji (University of Ilorin)
“Antimalarial & Hematological Evaluation of Ethanolic Extracts of Cleodendrum violaceum”
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| 16:30pm-17:00pm |
Dr Jean-Francois Trape (Institut de Recherché pour de Development, Senegal)
“Antimalarials and Malaria burden: Lesson from longitudinal studies””
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| 17:00pm-17:30pm |
Professor Wilfred Mbacham (University of Yaoundé, Cameroon)
“Managing Adverse Events & Effects during Malaria Trials”
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| 17:30pm-18:00pm |
Professor Issaka Sagara (University of Bamako, Mali)
“Dispersible tablet formulation of artemether-lumefantrine (Coartem®): Efficacy and safety in paediatric patients with acute uncomplicated Plasmodium falciparum malaria – a randomized, investigator-blinded, multicenter comparison with the crushed tablet”
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| 18:00pm – 18:45pm |
Panel Discussion”
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| 18:45pm- 19:00pm |
Coffee Break & Interactive Session
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Session 6: Vaccine Strategies
Chair: Professor Nadira Karunaweera ( University of Colombo , Sri Lanka )
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| 19:00 am - 19:30 pm |
Dr Volker Heussler (Bernhard-nocht Institute, Germany)
“Plasmodium Survival Strategies & Pre-erythrocytic Vaccine Development”
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| 19:30-20:00pm |
Godswill Anyasor (Babcock University, Nigeria)
“Artesunate opens rat liver mitochondrial membrane permeability (mmpt) pore”
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| 20:00-20:30pm |
Dr Roma Chilengi (Malaria Network Trust)
“Malaria Vaccine for Africa-Experience of AMANET R&D”
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| 20:30 pm – 21:00 pm |
Panel Discussion
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| 21:00-21:10pm |
Vote of Thanks
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21:10pm |
Symposium Ends
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